CHS — Medicago truncatula

Summary

MTR_2G058470, designated MtCHS or CHS, encodes a chalcone synthase, a type-III polyketide synthase bearing chalcone/stilbene synthase and thiolase-like domains. The enzyme exhibits chalcone isomerase, naringenin-chalcone synthase, dihydroflavanol 4-reductase, flavanone 4-reductase, flavonol synthase, and SUMO transferase activities. MtCHS is associated with chalcone, flavonoid, anthocyanin, and phenylpropanoid biosynthesis, as well as responses to UV-B, gravity, and auxin polar transport. It localizes to the cytosol, nucleus, endoplasmic reticulum, and tonoplast. The gene is linked to traits including seed coat color, fruit color, anthocyanin content, drought tolerance, salt stress tolerance, root-knot nematode resistance, and flowering time. Related genes in other species are linked to flavonoid production, UV-B sensitivity, male fertility, and phenylpropanoid pathway activity.