LOX — Lactuca sativa

Summary

LsLOX, encoded by gene LSAT_V11C100026710 on lettuce chromosome 1, is a lipoxygenase with linoleate 13S-lipoxygenase and phytoene dehydrogenase activities, and oxidoreductase activity that incorporates molecular oxygen. It contains lipoxygenase and PLAT/LH2 domains and binds metal ions. The gene is associated with green leaf volatile biosynthesis, oxylipin anabolism, lipid oxidation, and responses to wounding, jasmonic acid, salicylate, and other organisms. It is also linked to fatty acid and terpenoid anabolism, triglyceride metabolism, translation elongation, and base excision repair. The product localizes to the chloroplast thylakoid and stroma. Additionally, LsLOX has been connected to nitrate content and nitrate transport. Studies of related genes in other species link the family to linoleate 13S-lipoxygenase activity (EC 1.13.11.12).