HSP70 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.6HG0633680, symbol HSP70, on barley chromosome 6H encodes an ATP-dependent protein folding chaperone of the Hsp70 family, possessing ATP hydrolase activity and heat shock protein binding capability. The gene is associated with protein refolding, the ERAD pathway, and the unfolded protein response, as well as responses to heat, stress, virus infection, and immune and innate immunity processes. It has been linked to pollen tube growth, lipid metabolism, and response to thirst. The encoded protein localises to the ER lumen and chaperone complex, chloroplast membrane, cytoplasm, nucleus, and axonemal central pair projection. Studies of related genes in other species link the family to endoplasmic reticulum stress responses.