ERD2 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.5HG0526250 (HvERD2) on barley chromosome 5H encodes a member of the Hsp70 family of ATP-dependent protein folding chaperones, characterised by an ATPase nucleotide-binding domain and a peptide-binding domain. The gene is associated with a wide range of molecular functions including calcium-dependent phospholipid binding, DXP-synthase activity, and Hsp90 binding, and is linked to processes such as protein folding in the endoplasmic reticulum, RuBisCO assembly, and mitochondrial protein import. It has been connected to agronomically important traits including grain filling period, biomass yield, photosynthetic ability, carotenoid content, and responses to temperature, salt, and chilling. Additionally, HvERD2 is associated with pathogen defense responses, including upregulation of defense response to oomycetes and cucurbit downy mildew response, and with plant development traits such as shoot apical meristem development and cell cycle regulation.