PCNA — Glycine max

Summary

GmPCNA (GLYMA_08G334900V4) on soybean chromosome 8 encodes a proliferating cell nuclear antigen, a DNA sliding clamp that acts as a processivity clamp for DNA-directed DNA polymerase and also exhibits histone H3K27 methylase, SUMO transferase, and damaged DNA binding activities. The gene is associated with DNA replication, repair, and chromatin remodeling processes, including bypass DNA synthesis, mismatch repair, and double-strand break repair via synthesis-dependent strand annealing. It is linked to traits such as radiation response, UV light sensitivity, oxidative stress response, abscisic acid sensitivity, flowering time, root morphology, and stomatal opening. Associations with cell cycle control, nuclear genome stability, heterochromatin condensation, and transposon silencing have been noted. Studies of related genes in other species connect the PCNA family to DNA repair, cadmium response, immune response, and thermo-resilience.