IRT1 — Glycine max

Summary

GmIRT1 (GLYMA_07G223200V4) on soybean chromosome 7 encodes a member of the ZIP metal transporter family with copper, zinc, iron, manganese, and cadmium ion transmembrane transporter activity, as well as ubiquitin and phosphoinositide binding. The gene is associated with metal ion transport, including nickel, zinc, manganese, and cadmium transport, and with cellular and multicellular iron ion homeostasis. It has been linked to seed color and seed coat color, photosynthetic rate, chlorophyll content, and plant growth and development traits. Associations include cadmium detoxification, iron deficiency tolerance, metal accumulation, root and leaf development, chloroplast development, disease resistance, and circadian period length. The gene is also connected to endosome membrane budding, MVB formation, regulation of DNA replication, pH reduction, and downregulation of abscisic acid-mediated signaling, with localization to the plasmalemma, endosome, late endosome membrane, and nucleus.