FAD2 — Daucus carota subsp. sativus

Summary

DCAR_019787, symbol DcFAD2 on carrot chromosome 5, encodes a fatty acid desaturase with oleate Δ12-hydroxylase, omega-6 fatty acid desaturase and monooxygenase activities. The product is an oxidoreductase acting on paired donors with molecular oxygen reduction, localised to the endoplasmic reticulum membrane. DcFAD2 is associated with unsaturated fatty acid anabolism, fatty acid metabolism and lipid metabolism, and participates in glycolipid desaturation reactions including conversions of 18:1-16:1-MGDG to 18:2-16:1-MGDG and 18:1-16:0-DGDG to 18:2-16:0-DGDG. Related genes in other species link the family to delta-12 desaturase and hydroxylase activities (EC 1.14.19.33, 1.14.19.34, 1.14.18.4), though these specific enzyme classifications are not yet established for carrot DcFAD2.