PPAR — Daucus carota subsp. sativus

Summary

DCAR_016676 (symbol PPAR, also known as DcPGDH2) on carrot chromosome 5 encodes a protein with a D-isomer-specific 2-hydroxyacid dehydrogenase NAD-binding domain and NAD(P)-binding domain superfamily, annotated with multiple oxidoreductase activities including phosphoglycerate dehydrogenase, glyoxylate reductase, hydroxypyruvate reductase, and formate dehydrogenase activities. The gene is associated with photorespiration, the oxidative photosynthetic carbon pathway, fatty acid oxidation and anabolism, lipid metabolism, glucose metabolism, formate breakdown, and fat cell differentiation. Its product localizes to mitochondria, cytosol, and chloroplasts. Studies of related genes in other species link the family to glycerate dehydrogenase and D-lactate dehydrogenase activities (EC 1.1.1.29, 1.1.1.28), and to associations with nitrate, flavonoid, and carotenoid content.