M2 — Daucus carota subsp. sativus

Summary

DCAR_013872, designated DcM2 and located on carrot chromosome 4, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) with cis-trans proline isomerase activity and cyclosporin A binding capacity. This gene is associated with protein folding and regulation of protein refolding, as well as responses to abscisic acid, salt, and mannitol. It is linked to activation of the salinity response, sensitization, and carotenoid anabolism. The encoded protein localizes to the chloroplast stroma, cytosol, cytoplasm, nucleus, and plasmalemma. Related genes in other species link the family to the enzyme class EC 5.2.1.8, a peptidyl-prolyl cis-trans isomerase.