SDH — Daucus carota subsp. sativus

Summary

DCAR_013190 (SDH) on carrot chromosome 4 encodes a short-chain dehydrogenase/reductase (SDR) family protein with an NAD(P)-binding domain. The enzyme exhibits multiple annotated activities including momilactone-A synthase, zerumbone synthase, (+)-borneol dehydrogenase, secoisolariciresinol dehydrogenase, xanthoxin dehydrogenase, and aldo-keto reductase activity, all NAD- or NADP-dependent. The gene is associated with terpenoid, monoterpenoid, phenylpropanoid, lignan, and abscisic acid biosynthesis, as well as (+)-camphor anabolism and spore germination. It is linked to responses to UV, jasmonic acid, and wounding, and to protein homotetramerization. The product localizes to mitochondria and cytosol. Studies of related genes in other species connect the SDR family to momilactone and borneol dehydrogenase activities.