M2 — Daucus carota subsp. sativus

Summary

DCAR_007378, also known as DcM2, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) located on carrot chromosome 2. The enzyme possesses cis-trans proline isomerase activity and binds cyclosporin A. This gene is associated with protein folding, regulation of protein refolding, and responses to abiotic stresses including salt, mannitol, and abscisic acid. It is linked to carotenoid anabolism and activation of the salinity response. The product localizes to the chloroplast stroma, cytosol, cytoplasm, nucleus, and plasmalemma. Studies of related genes in other species link this family to peptidyl-prolyl isomerase activity (EC 5.2.1.8).