MLO — Cucumis sativus

Summary

CSA_5G623470, designated MLO and also known as MLO2, MLO6, and CsPMR2, encodes a member of the MLO protein family in cucumber (Cucumis sativus) on chromosome 5. The product is associated with calmodulin binding and protein binding, and is localized to the membrane, plasmalemma, Golgi complex, and plasmodesmata. This gene is linked to defense responses, including immune response, response to fungi and bacteria, and downregulation of defense response, as well as cell wall thickening, calcium signaling, and ABA signaling. It has been connected to wheat powdery mildew disease response, Botrytis cinerea resistance, leaf senescence, callose deposition, and systemic acquired resistance. Studies of related MLO genes in other species link the family to powdery mildew resistance and susceptibility, bacterial wilt susceptibility, heat tolerance, and ozone tolerance.