CAD2 — Cucumis sativus

Summary

CSA_5G153150 (CAD2/GSH1) on cucumber chromosome 5 encodes a glutamate--cysteine ligase (EC 6.3.2.2). The gene is associated with glutathione anabolism, and its product localizes to the chloroplast stroma, plastid, and cytosol. In cucumber, GSH1 has been linked to phenanthrene stress tolerance. The gene is associated with defense responses to insects and ozone, callose deposition, response to jasmonic acid, stomatal movement, fruit development and ripening, leaf development, adventitious root development, lignin anabolism, and cadmium response. Associations also include traits such as stem diameter, leaf size, photosynthetic rate, and resistance to downy mildew, Alternaria brassicicola, and other pathogens, as well as cadmium and chilling tolerance. Studies of related genes in other species link the family to glutathione content, cadmium sensitivity, and flowering time.