LOX — Cucumis sativus

Summary

CsLOX, encoded by the cucumber gene CSA_4G287530 on chromosome 4, is a lipoxygenase family protein containing lipoxygenase and PLAT/LH2 domains. It exhibits linoleate 13S-lipoxygenase, phytoene dehydrogenase, peroxidase, and salicylic acid-binding activities, and is associated with the lipoxygenase pathway, oxylipin and jasmonic acid biosynthesis, lipid oxidation, and responses to herbivory and high light intensity. The protein localizes to chloroplast thylakoids, stromules, and stress granules. CsLOX is linked to agronomically important traits including seed yield, carotenoid and chlorophyll content, photosynthetic rate, plant height, stem diameter, leaf number, and photoperiod-sensitive flowering. It is also associated with wound response, jasmonic acid accumulation, drought resistance, herbivore resistance, and tolerance to cadmium and heat stress. Studies of related genes in other species connect the family to oxylipin biosynthesis, green leaf volatile production, and resistance to herbivores and fungal pathogens.