F3H — Cucumis sativus

Summary

CSA_3G002800 (F3H) in cucumber encodes a naringenin,2-oxoglutarate 3-dioxygenase, also known as flavanone 3-dioxygenase, which belongs to the Fe2OG dioxygenase superfamily and exhibits chalcone isomerase, flavonol synthase, and flavanone 3-dioxygenase activities. This gene is associated with flavonoid, anthocyanin, and proanthocyanidin biosynthesis, as well as responses to UV-B, hormones, and fungal molecules. It has been linked to traits including flavonoid and anthocyanin content, UV-B sensitivity, powdery mildew resistance, pollen viability and thermotolerance, lateral root formation, root hair development, and cold acclimation. The encoded protein localizes to the cytosol, nucleus, endoplasmic reticulum, and tonoplast. Studies of related genes in other species connect the F3H family to seed coat pigmentation, UV-B tolerance, flavonol production, and stress tolerance.