HMA1 — Cucumis sativus

Summary

CsHMA1 (CSA_2G060450) on cucumber chromosome 2 encodes a P-type ATPase of the IB subfamily with heavy-metal-associated domains, annotated with copper, zinc and cadmium transporter activities as well as histone methylase activity. The gene is associated with detoxification of copper, zinc and cadmium ions, cellular copper and zinc homeostasis, and responses to cobalt and toxic substances. It has been linked to traits including copper sensitivity, drought tolerance, high-temperature stress response, chlorophyll content, plant height, flowering time, leaf senescence, stomatal opening and closure, germination rate, root and seedling development, and disease tolerance. Localisation evidence connects the product to the vacuolar membrane, Golgi membrane, chloroplast thylakoid membrane and chromatin. Related genes in other species are linked to copper transport, zinc and cadmium detoxification, photosynthesis under high light, and oxidative stress tolerance.