NPP5 — Cucumis melo
Summary
MELO3C014676.2, designated CmNPP5 on melon chromosome 6, encodes a protein serine/threonine phosphatase (EC 3.1.3.16) with a calcineurin-like phosphoesterase domain, belonging to the PP2A family. The gene is associated with protein phosphatase regulator activity and kinase binding. It has been linked to TOR signaling, protein dephosphorylation, negative regulation of leaf senescence, and regulation of nitrogen utilization. CmNPP5 is associated with brassinosteroid signaling, seed development, and root development traits, including primary root development and root mass density. Associations also include response to cold and abscisic acid, seed maturation, seed germination, leaf size, and ethylene biosynthesis. The protein localizes to the PP2A complex, nucleus, cytosol, and nucleolus. Studies of related genes in other species link the family to drought tolerance, root length, and stomatal opening.
Annotations
- Chromosome
- 6
- Related genes
- NPP5, TIFY8, PP2A-4, PP2A-3, TAP46, PP2A
- GO terms
- Regulation Of Nitrogen Utilization, downregulation of seed germination, Protein Dephosphorylation, protein phosphatase activity, PP2A complex, TOR Signaling, Protein Phosphatase Regulator Activity, Protein Phosphatase Binding
- Publications
- 30825377, 16626458, 14551330, PMID:17317660, 18315867, 28627464, PMID:30833711, PMID:25293756
- Traits
- leaf senescence, seedling development, protein phosphorylation, other miscellaneous trait, Altered ABA Sensitivity, Reduced Seed Germination, Increased Root Growth Sensitivity, Short Primary Root with Disrupted Root Tip Organization, Longer Primary Root, Reduced Columella Stem Cell Differentiation, Altered ABA Sensitivity, Agravitropic Roots