M2 — Cucumis melo

Summary

MELO3C013375.2 (CmM2) on melon chromosome 2 encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) with additional annotated molecular functions including GTP:GDP antiporter activity, U5 and U2 snRNA binding, L-serine O-acetyltransferase activity, peroxidase activity, and salicylic acid, histone, and chromatin binding. The gene is associated with diverse biological processes such as protein proline isomerization, regulation of ARF protein signal transduction, alternative mRNA splicing, response to light intensity and sulfate starvation, and cysteine anabolism. It has been linked to numerous agronomic traits including variegated leaf, net photosynthetic rate, respiration rate, sucrose content, starch grain synthesis, chloroplast development, root hair length, meristem identity, herbicide sensitivity, and temperature stress response. Localization evidence connects the product to the Golgi stack, thylakoid lumen, proteasome, and secretory vesicles. Studies of related genes in other species link the family to embryo patterning, hydrotropism, cold stress tolerance, and drought response.