ALS — Cicer arietinum

Summary

CaALS (LOC101513951) on chickpea chromosome 1 encodes an acetolactate synthase (ALS) enzyme, also known as AHAS, which possesses acetolactate synthase activity, 2-hydroxyacyl-CoA lyase activity, pyruvate decarboxylase activity, and binds thiamine pyrophosphate, FAD, and magnesium. The enzyme localises to the chloroplast stroma and the acetolactate synthase complex. CaALS is associated with branched-chain amino acid biosynthesis, valine biosynthesis, fatty acid alpha-oxidation, and response to herbicide. The gene is linked to herbicide tolerance, particularly through the G121A substitution. Related genes in other species are associated with herbicide resistance, including sulfonylurea and imidazolinone tolerance, as well as seed weight, plant height, nitrogen content, and salt response.