NDH1 — Cicer arietinum

Summary

CaNDH1 (LOC101507693) on chickpea chromosome 4 encodes a protein with NAD-dependent malate dehydrogenase domains, including Malate_DH_NAD-dep_euk and Malate_DH_type2, and is annotated with L-malate dehydrogenase (NADP+) and NAD-L-malate dehydrogenase activities. The gene is associated with the TCA cycle, malate and oxaloacetate metabolism, redox sensing, and responses to cold acclimation, freezing, and nitrogen or potassium starvation. It has been linked to seed maturation, leaf growth and senescence, root and pistil morphology, respiration rate, and stress tolerance traits including cold tolerance, nematode resistance, and bacterial resistance. Localisation evidence connects the product to the chloroplast stroma, plastid, ER, Golgi, vacuole, apoplast, and plasmodesmata. Studies of related genes in other species link the family to leaf size variation.