CYP81E5 — Cicer arietinum

Summary

CYP81E5 on chickpea chromosome 1 encodes a cytochrome P450 monooxygenase with piperitol synthase, 4'-methoxyisoflavone 2'-hydroxylase, isoflavone 2'-hydroxylase, and isoflavone 3'-hydroxylase activities, binding heme and iron. It is associated with secondary metabolism and immune response, and localises to the endoplasmic reticulum membrane. Related genes in other species link the family to isoflavone hydroxylation reactions (EC 1.14.14.88–90, 1.14.19.74).