ICDH — Capsicum annuum

Summary

CaICDH (T459_26301) on pepper chromosome 10 encodes an isopropylmalate dehydrogenase-like domain-containing protein with NADP isocitric dehydrogenase activity, and NAD, magnesium, copper, protein phosphorylated amino acid, metal, ATP, and protein binding activities. The gene is associated with the TCA cycle, glyoxylate cycle, cellular respiration, NADP metabolism, isocitrate metabolism, detoxification, fruit ripening, microsporogenesis, cell growth and death, brassinosteroid-mediated signalling, and defence response to bacteria. It has been linked to pungency, cytoplasmic male sterility, respiration and photosynthetic rates, root morphology, nitrogen metabolism, histone methylation, redox homeostasis, and leaf hydraulic conductivity. The protein localises to chloroplast thylakoid and stroma, plastid, mitochondria, cytosol, apoplast, plasmodesma, and plasmalemma. Studies of related genes in other species connect the family to seed weight, drought and salt tolerance, disease tolerance, chlorophyll content, and oxidative stress response.