ICDH — Capsicum annuum

Summary

CaICDH (T459_20858) on pepper chromosome 7 encodes an isocitric dehydrogenase with NAD and NADP isocitric dehydrogenase activities, NAD and ATP binding, and metal-binding properties including copper and magnesium. The protein localises to chloroplasts, mitochondria, plastids, cytosol, and plasmalemma. CaICDH is associated with the TCA cycle, glyoxylate cycle, cellular respiration, NAD and NADP metabolism, isocitrate metabolism, detoxification, fruit ripening, microsporogenesis, cell growth and death, brassinosteroid-mediated signalling, and defence response to bacteria. It has been linked to pungency, cytoplasmic male sterility, respiration and photosynthetic rates, root morphology, nitrogen metabolism, redox homeostasis, and leaf hydraulic conductivity. Studies of related genes in other species connect the family to seed weight, drought and salt tolerance, disease tolerance, chlorophyll content, and oxidative stress response.