ICDH — Capsicum annuum

Summary

CaICDH (T459_19181) on pepper chromosome 7 encodes a protein with isocitrate dehydrogenase NADP and isopropylmalate dehydrogenase-like domains, possessing NADP isocitric dehydrogenase and NAD isocitric dehydrogenase activities, along with NAD, ATP, copper, and metal binding capabilities. The gene is associated with the TCA cycle, glyoxylate cycle, cellular respiration, NAD and NADP metabolism, and isocitrate metabolism. It is linked to fruit ripening, microsporogenesis, cell growth and death, brassinosteroid-mediated signalling, defence response to bacteria, and detoxification. The gene is associated with pungency, cytoplasmic male sterility, photosynthetic and respiration rates, root morphology, nitrogen metabolism, redox homeostasis, and leaf hydraulic conductivity. Localisation evidence places the product in chloroplast thylakoid and stroma, plastids, mitochondria, cytosol, apoplast, and plasmodesmata. Studies of related genes in other species link the family to seed weight, drought and salt tolerance, chlorophyll content, and disease tolerance.