MLO — Capsicum annuum

Summary

The pepper gene T459_15481, symbol MLO and preferred name MLO2 on chromosome 5, encodes a calmodulin-binding protein. It is associated with defense responses to bacteria and fungi, downregulation of defense response, virus-induced PTGS, cell death, and regeneration. The protein localizes to the membrane, plasmalemma, Golgi complex, plasmodesma, mitochondria, and extracellular space. MLO2 is linked to wheat powdery mildew disease response, callus induction, high temperature stress response, and disease tolerance. Observed phenotypes include Botrytis cinerea resistance, leaf senescence, systemic acquired resistance, and callose deposition. Related genes in other species link the MLO family to powdery mildew resistance and disease resistance, bacterial wilt susceptibility, and powdery mildew susceptibility.