4CL1 — Capsicum annuum

Summary

T459_10634 (4CL1) on pepper chromosome 3 encodes a putative 4-coumarate-CoA ligase 2, a member of the AMP-binding superfamily with benzoate-CoA ligase, trans-feruloyl-CoA synthase, (E)-caffeate-CoA ligase, trans-cinnamate-CoA ligase, 4-coumarate-CoA ligase and CoA-ligase activities, and binds ATP. The gene is associated with phenylpropanoid, cinnamic acid, ferulate and phosphate metabolism, phytoalexin and anthocyanin biosynthesis, lignin anabolism, and suberin biosynthesis. It is linked to fruit development and ripening, placentation, circadian rhythm, signal transduction, defense response, response to wounding and jasmonic acid, and localises to the cytosol and cytoplasm. Associations with pungency, fruit color, fruit weight and anthocyanin content have been noted. Studies of related genes in other species link the family to 4-coumarate-CoA ligase (EC 6.2.1.12) and related enzyme activities.