HIR1 — Capsicum annuum

Summary

CaHIR1 (T459_04791) on pepper chromosome 2 encodes a hypersensitive-induced response protein 4 containing a Band7/SPFH domain. The gene is associated with telomeric repeat binding, histidine kinase binding, and ATP hydrolase activity, and is linked to programmed cell death, the hypersensitive response, and defence responses to bacteria, fungi, and oomycetes. It has been connected to detection of bacteria, signal transduction, and regulation of telomere maintenance, as well as to traits including bacterial disease response, disease tolerance, seed viability, and flowering time. Localisation evidence places the product at the plasmalemma, tonoplast, plastid, mitochondria, Golgi complex, plasmodesmata, stress granules, and cytosol. Studies of related genes in other species link the family to innate immunity, Pseudomonas syringae resistance, and telomere length regulation.