KCS2 — Camelina sativa

Summary

CsKCS2 (CSA14G005360) on Camelina sativa chromosome 14 encodes a 3-ketoacyl-CoA synthase, a member of the FAE1-type polyketide synthase family with acetoacetyl-CoA reductase, trans-2-enoyl-CoA reductase (NADPH), ketoreductase, and 3-hydroxyacyl-CoA dehydratase activities (EC 2.3.1.199). The gene is associated with very-long-chain fatty acid metabolism and anabolism, wax anabolism, suberin biosynthesis, cutin-based cuticle development, sphingolipid metabolism, and trichome papilla formation and branching. It is linked to cuticular wax biosynthesis, root suberin biosynthesis, and phenotypes including glossy stems, reduced root growth, abnormal suberin layers, and conditional male sterility. Associations extend to drought and salt tolerance, high temperature stress response, root morphology traits, leaf composition, and plant growth and development. The protein localizes to the fatty acid elongase complex, endoplasmic reticulum membrane, mitochondria, cytosol, and nucleus. Studies of related genes in other species link the family to very-long-chain fatty acid biosynthesis, cuticular wax formation, pollen fertility, and root hair elongation.