HMA2 — Camelina sativa
Summary
CSA11G013310, designated HMA2 and also known as CsHMA3, encodes a P-type ATPase of the IB subfamily with cation-transporting ATPase activity, including cadmium-exporting, copper, zinc, and calcium transporter activities, and is localized to the vacuolar membrane, Golgi membrane, and plasmalemma. The gene is associated with detoxification of cadmium and copper ions, copper ion homeostasis, and membrane transport, as well as defense responses to bacteria, including detection of bacteria and hypersensitive response-programmed cell death. It has been linked to leaf width and shape, bacterial disease response, disease tolerance, lead tolerance, cadmium detoxification, zinc homeostasis, shoot cadmium concentration, and leaf cadmium accumulation. Studies of related genes in other species connect the family to cadmium and zinc tolerance, cobalt tolerance, and cadmium transport.
Annotations
- Chromosome
- 11
- Related genes
- HMA3, HMA2, RPS2
- GO terms
- Response To Toxic Substance, P-type ATPase activity, Detoxification Of Copper Ion, ADP Binding, plasmalemma, P-type Monovalent Copper Transporter Activity, metal binding, copper binding
- Publications
- 30300945, 24377444, 16608451, 17447913, 22880057, 31362467, 17181774, 31550400
- Traits
- disease resistance, cadmium transport, cadmium tolerance, hypersensitive cell death response, other miscellaneous trait, Susceptible to Pseudomonas with avrRpt2, Lacks Hypersensitive Response, Impaired RPM1-Mediated Resistance to Bacterial Effectors, Susceptible to Pseudomonas with avrRpm1, avrB, or avrRpt2