PPAR — Camelina sativa

Summary

CSA07G039210, designated PPAR on Camelina sativa chromosome 7, encodes a D-isomer-specific 2-hydroxyacid dehydrogenase family protein with NAD(P)-binding domains. The enzyme exhibits multiple oxidoreductase activities, including formate dehydrogenase (NAD+), phosphoglycerate dehydrogenase, hydroxypyruvate reductase, and glyoxylate reductase activities. The gene is associated with photorespiration and the oxidative photosynthetic carbon pathway, as well as formate breakdown. It has been linked to hypersensitivity, immune response, and homeostasis. The protein localises to mitochondria and cytosol. Studies of related genes in other species connect the family to similar oxidoreductase functions and photorespiratory metabolism.