ADR2 — Camelina sativa

Summary

CsADR2 (CSA05G063300) on Camelina sativa chromosome 5 encodes a protein with TIR, NB-ARC, and disease resistance domains, and has NADP nucleosidase, ATP hydrolase, ADP binding, ATP binding, protein homodimerization, and protein binding activities. The gene is associated with defense responses to oomycetes, fungi, insects, and other organisms, as well as programmed cell death, innate immunity, cellular response to UV, NAD breakdown, and signal transduction. It has been linked to disease resistance, basal immunity, UV stress resistance, and plant growth. The encoded protein localizes to the endoplasmic reticulum, plasma membrane, cytoplasm, and nucleus. Studies of related genes in other species link the family to white rust resistance and susceptibility to Pseudomonas syringae, while sequence similarity extends associations to wheat leaf rust response, UV-B sensitivity, salt response, and photochemical quenching.