CENH3 — Brassica oleracea var. botrytis

Summary

BoCENH3 (BOLND125_C08P072540.1) on cauliflower chromosome 8 encodes a centromere-specific histone H3 variant (CENP-A) with a histone-fold domain, annotated for structural chromatin constituent, DNA and methylated DNA binding, and ubiquitin-protein transferase activity. It is associated with centromere complex and kinetochore localization, and with biological processes including CENP-A-containing chromatin assembly, kinetochore assembly, meiotic chromosome separation, centromeric silencing, and double fertilization. The gene is linked to traits such as relative root length, root thickness, and flowering time, and to phenotypes including centromere hypomethylation, chromosome segregation, haploid induction, and clonal reproduction. Studies of related genes in other species connect the family to haploid production, uniparental genome elimination, centromere identity, meiotic genome stability, and flowering time.