ICK1 — Brassica oleracea var. botrytis

Summary

BoICK1, encoded by the cauliflower gene BOLND125_C08P051560.1_BOLND125_V1 on chromosome 8, is a cyclin-dependent kinase inhibitor belonging to the KRP (Kip-Related Protein) family. It possesses cyclin-dependent protein kinase inhibitor activity and is associated with ubiquitin ligase activity. The gene is linked to the regulation of cell cycle G1/S phase transition, mitotic entry, and symmetric cell division, as well as stomatal complex development, guard mother cell differentiation, and lateral root morphogenesis. BoICK1 has been connected to leaf and root morphology traits, including leaf attitude, size, and vein architecture, root thickness, and trichome morphology. It is also associated with disease tolerance, cytokinin sensitivity, and shoot and root meristem development. The protein localises to the nucleus, cytoplasm, preprophase band, and ubiquitin ligase complex. Studies of related genes in other species link the family to cell cycle arrest, endoreduplication, and virus susceptibility.