MBD7 — Brassica oleracea var. botrytis

Summary

BoMBD7, encoded by gene BOLND125_C03P013780.1 on cauliflower chromosome 3, is a methyl-CpG-binding domain protein with annotated protein arginine methyltransferase (PRMT) activity, histone acetyltransferase activity, and double-stranded methylated DNA binding. It is associated with chromatin modelling, RNA-directed DNA methylation (RdDM), and demethylation. The protein localises to the nucleus, chromocenter, cytoplasm, and plasmodesmata. BoMBD7 is associated with root morphology traits, DNA methylation levels, epigenetic and transcriptional gene silencing, and decreased tolerance to osmotic stress and abscisic acid. Related genes in other species link the family to methylated DNA binding, chromatin structure, and DNA methylation-induced gene silencing, and to hypermethylated differentially methylated regions and long roots on sucrose media.

Annotations

Chromosome
3
Related genes
MBD7, IDM3, PRMT11, IDM2, IDM1
GO terms
Histone Binding, PRMT activity, Nucleus, Cytoplasm, Demethylation, RdDM, GO:0032259, Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups
Publications
16132859, 12678558, 11599564, 15310832, 28441590, PMID:27470001, 12383089, PMID:21533090
Traits
other miscellaneous trait, Higher DNA methylation levels, Decreased Tolerance to Osmotic Stress and ABA, Hypermethylated DMRs, Long Roots on Sucrose Media, aLRLpMRL125, DNA methylation-induced gene silencing, methylated CpG binding, clim-gs9