IRT1 — Brassica oleracea

Summary

BoIRT1 (BOLC102_C07P055430.1_BOLC102_V1) on cabbage chromosome 7 encodes a member of the ZIP family of metal transporters, possessing iron channel activity and transmembrane transporter activities for copper, manganese, zinc, and cadmium ions. The gene is associated with metal homeostasis, iron deficiency tolerance, and the regulation of cellular response to basic pH. BoIRT1 is linked to photosynthetic rate, chlorophyll content, plant growth and development trait, root development, leaf development, and disease resistance. It is also associated with cadmium, zinc, and iron accumulation and uptake, as well as responses to chromium, uranium, and salt stress. The encoded protein localises to the plasma membrane, endosomes, and the trans-Golgi network, and is associated with auxin anabolism and downregulation of abscisic acid mediated signaling. Studies of related genes in other species link the family to iron acquisition, nickel accumulation, and cadmium sensitivity.