GSM1 — Brassica oleracea

Summary

BoGSM1 (GSM1) on chromosome 4 of cabbage (Brassica oleracea) encodes a protein with methylthioalkylmalate synthase and 2-isopropylmalate synthase activities, placing it in the family of enzymes that catalyse the condensation step in methionine chain elongation for aliphatic glucosinolate biosynthesis. The gene is associated with glucosinolate anabolism, response to insect, nodulation, leaf development, and response to thirst, and its product localises to the chloroplast. Associations with stem thickness and leaf width have been noted, and the gene is linked to glucosinolate composition, aliphatic glucosinolate side-chain length, aliphatic glucosinolate content, glucose sensitivity, and leucine biosynthesis. Studies of related genes in other species link the family to seedling growth and altered glucosinolate composition.