NIM1 — Brassica napus

Summary

BnNIM1 (NPR1, NIM1) on chromosome A09 of oilseed rape encodes a transcriptional co-regulator with oxidoreductase activity acting on a sulfur group of donors, disulfide as acceptor, and salicylic acid binding. The protein contains BTB/POZ, ankyrin repeat, and NPR1/NIM1-like domains. It is associated with regulation of systemic acquired resistance, salicylic acid-mediated signaling, defense responses to bacteria and insects, and induced systemic resistance via jasmonic acid. Localization evidence links it to the nucleus, cytosol, plasmodesmata, and stress granules. The gene has been connected to numerous agronomic traits including bacterial blight disease resistance, drought sensitivity, photosynthetic rate, stomatal resistance, stem senescence, and responses to stripe rust, powdery mildew, and Cercospora leaf spot. Studies of related genes in other species link it to pathogen resistance, systemic acquired resistance, and salicylic acid-responsive gene expression.