CHM — Brassica juncea

Summary

BJUUNNG05580S (symbol CHM, also known as BjCHM or MSH1) in Indian mustard (Brassica juncea) encodes a protein with domains characteristic of a mitochondrial DNA mismatch repair MutS homologue, including a GIY-YIG endonuclease domain and a P-loop NTPase domain. The product exhibits mispair binding, ATP-dependent DNA damage sensor activity, and double-stranded DNA binding. It is associated with mitochondrion DNA recombination, negative regulation of DNA metabolism, homologous chromosome segregation, chiasma assembly, resolution of meiotic recombination intermediates, anther development, and response to heat. The protein localises to mitochondria, plastids, the thylakoid membrane, the nucleus, and the MSH2/MSH6 complex. This gene has been linked to cytoplasmic male sterility, leaf variegation, plastid alterations, and a wide range of stress tolerance and growth traits including heat, cold, salt, and drought tolerance, as well as flowering time, shoot branching, and stomatal density.