NRAMP4 — Brassica juncea

Summary

BjNRAMP4 (BJUB06G44320S) encodes a member of the NRAMP family of metal ion transmembrane transporters, with molecular functions including manganese ion transmembrane transporter activity. The gene is associated with the transport of lead, manganese, iron, and cadmium ions, as well as the regulation of vacuolar transport, cellular metal ion homeostasis, and responses to iron and metal stress. It is linked to defence responses against bacteria and nematodes, and to the positive regulation of reactive oxygen species metabolism. The encoded protein localises to the tonoplast, vacuolar membrane, trans-Golgi network membrane, and plasma membrane. Associations with photosynthetic rate, seed germination, iron remobilisation and localisation in seeds, copper homeostasis, and growth under manganese deficiency have been observed. Related genes in other species are linked to vacuolar iron transport, iron deficiency sensitivity, manganese homeostasis, and pathogen resistance.