PPAR — Brassica juncea

Summary

BJUA09G05310S (symbol PPAR) on Indian mustard chromosome A09 encodes a protein with a D-isomer 2-hydroxyacid dehydrogenase catalytic domain and exhibits multiple enzyme activities including (2R)-hydroxyphenylpyruvate reductase, glyoxylate reductase, hydroxypyruvate reductase, and D-lactate dehydrogenase activity, along with NAD binding and DNA-binding transcription factor activity. The gene is associated with photorespiration, fatty acid oxidation, lipogenesis, fat cell differentiation, heat generation, angiogenesis, myelination, regeneration, and regulation of DNA-templated transcription. Its product localises to both the cytosol and nucleus. Studies of related genes in other species link the family to various dehydrogenase activities (EC 1.1.1.237, 1.1.1.110, 1.1.1.26, 1.1.1.28, 1.1.1.79), though these associations are not yet established for this specific gene.