GSH1 — Brassica juncea

Summary

BJUA03G12170S (GSH1) on chromosome A03 of Indian mustard (Brassica juncea) encodes a glutamate-cysteine ligase, the enzyme that catalyses the first step of glutathione biosynthesis. The protein contains a plant-type glutamylcysteine ligase domain and a GCS2 domain, and has been annotated with glutamate-cysteine ligase activity and ATP binding. The gene is associated with glutathione anabolism, sulfur metabolism, oxoacid metabolism, and homeostasis, and its product localises to the chloroplast. Studies of related genes in other species link the family to the same EC number (6.3.2.2).