ERD2 — Brachypodium distachyon

Summary

BdERD2 (BRADI_4G04220V3) on chromosome 4 of Brachypodium distachyon encodes a member of the Hsp70 family of heat shock proteins, characterized by an ATPase nucleotide-binding domain and the HSP70 peptide-binding superfamily domain. The product exhibits ATP-dependent protein folding chaperone activity and has been annotated with diverse molecular functions including calcium-dependent phospholipid binding, DXP-synthase activity, and Hsp90 binding. BdERD2 is associated with numerous biological processes such as protein folding in the endoplasmic reticulum, cytosol-to-ER transport, RuBisCO assembly, and cellular responses to salicylate and humidity. It is linked to agronomically important traits including grain filling period, spikelet number, biomass yield, photosynthetic ability, carotenoid content, and responses to temperature, salt, and chilling. Additional associations include leaf morphology, inflorescence development, and defense responses to oomycetes and downy mildew.