HSP70 — Brachypodium distachyon

Summary

BRADI_3G53100V3 (BdHSP70) encodes a heat shock 70 kDa protein family member with ATP-dependent protein folding chaperone activity, adenyl-nucleotide exchange factor activity, and ATP hydrolase activity. The gene is associated with protein folding in the endoplasmic reticulum, the ERAD pathway, auxin transport, heat acclimation, stress response, pollen tube growth, and virus-induced post-transcriptional gene silencing. It has been linked to thermotolerance, heat shock response, wound response, abiotic stress response, and photosynthetic rate. The encoded protein localizes to the ER lumen, ER chaperone complex, tonoplast, Golgi complex, and secretory vesicles. Studies of related genes in other species connect the HSP70 family to grain yield, grain dimensions, spikelet number, heat tolerance, stem rust and stripe rust resistance, water use efficiency, and carotenoid content.