AXR6 — Brachypodium distachyon

Summary

BdAXR6 (BRADI_3G15900V3) on chromosome 3 of Brachypodium distachyon encodes a cullin family protein with ubiquitin ligase complex scaffold activity, NEDD8 transferase activity, and auxin receptor activity. This gene is associated with the regulation of protein ubiquitination, ethylene biosynthetic process, post-embryonic root development, and gibberellic acid-mediated signalling. It has been linked to responses to organophosphorus, potassium ions, and DNA damage, as well as stem cell renewal and microtubule severing. The encoded protein localises to the CRL complex, CSN, and nucleotide-excision repair complex. Associations with agronomically relevant traits include seed shattering, bacterial blight disease resistance, Cercospora leaf spot response, rice leaf sheath blight disease response, and photoperiod sensitivity. Studies of related genes in other species connect the family to drought stress, ABA response, UV-B tolerance, and grain yield.