BIP — Brachypodium distachyon

Summary

BRADI_3G01477V3 (BdBIP) encodes a member of the Hsp70 family of ATP-dependent protein folding chaperones, containing the characteristic HSP70 peptide-binding and ATPase domains. In Brachypodium distachyon, BdBIP is associated with the unfolded protein response, ER stress response, ERAD pathway, and protein refolding. It has been linked to diverse traits including spikelet number, root hair length, flowering time, leaf senescence, photosynthetic rate, stomatal resistance, osmotic and temperature stress responses, abscisic acid and auxin sensitivity, disease tolerance, and male fertility. The gene product localizes to the ER lumen, ER chaperone complex, transport vesicles, and nuclear envelope. Studies of related genes in other species connect the BIP family to seed storage protein accumulation, grain yield components, endosperm development, and stress acclimation.