HSP70 — Brachypodium distachyon

Summary

BRADI_2G23250V3 (HSP70, BdCTHSP70-1) on chromosome 2 of Brachypodium distachyon encodes a heat shock protein 70 family chaperone with ATP hydrolase activity, ATP binding, and heat shock protein binding functions. It is associated with protein folding in the endoplasmic reticulum, the ERAD pathway, the ER unfolded protein response, protein refolding, and heat acclimation. The gene is also linked to auxin transport, basipetal auxin polar transport, auxin signaling, amino acid membrane transport, and response to virus and stress. Its product localizes to the ER chaperone complex, ER lumen, cytoplasm, nucleus, chloroplast membrane, tonoplast, and membrane. Studies of related genes in other species link the family to grain yield, grain weight, grain protein content, spikelet fertility, plant height, root length, seed germination, heat tolerance, drought tolerance, and salt response.