AKT1 — Beta vulgaris subsp. vulgaris

Summary

BVRB_6G137140, designated AKT1, encodes a protein with ankyrin repeat and kinase-like domains that exhibits Kir channel activity, voltage-sensitive potassium channel activity, protein serine/threonine kinase activity, ubiquitin ligase activity, identical protein binding, zinc binding, and ATP binding. In sugar beet, this gene is associated with keratinocyte proliferation, epithelial-mesenchymal transition, wound healing, immune response, hypersensitive response-programmed cell death, response to oxidative stress, and protein ubiquitination. The encoded protein localizes to monoatomic ion channel complexes and the endoplasmic reticulum membrane. Studies of related genes in other species link this family to potassium channel function and serine/threonine kinase activity.