HSP70 — Beta vulgaris subsp. vulgaris

Summary

BVRB_1G001090 (HSP70) in sugar beet (Beta vulgaris subsp. vulgaris) chromosome 1 encodes a member of the heat shock protein 70 family, a chaperone with ATP hydrolase activity that binds ATP and heat shock proteins, and is annotated as a protein folding chaperone. The gene is associated with protein refolding, the ERAD pathway, the unfolded protein response, detoxification, and responses to stress, heat, and virus, as well as immune response. It is also linked to cytoskeleton and actin cytoskeleton organization, glycan biosynthesis, and carbohydrate metabolism. The encoded protein localizes to the ER chaperone complex, ER lumen, chloroplast membrane, membrane, cytoplasm, and nucleus, and is associated with axonemal central pair projection. Additionally, HSP70 is associated with zinc concentration. Studies of related genes in other species link the family to ER stress responses.