HSP70 — Asparagus officinalis

Summary

A4U43_C10F5900 (HSP70) on asparagus chromosome 10 encodes an uncharacterized protein with a heat shock 70 family domain and ATPase domain, annotated with ATP hydrolase activity, ATP binding, heat shock protein binding, and protein folding chaperone activity. The gene is associated with response to heat, protein refolding, protein folding, the ERAD pathway, the ER unfolded protein response, steroidogenesis, progesterone anabolism, lipid metabolism, homeostasis, and memory. Its product localises to the ER lumen, ER chaperone complex, chloroplast stroma, mitochondria, cytoplasm, nucleus, membrane, and mediator complex. Studies of related genes in other species link the family to heat shock 70 kDa proteins including BiP, HSP1, and mitochondrial chaperones.